Research Articles
Chromosomal Instability: The Engine of Metastasis Initiation and Emerging Therapeutic Strategies
This article provides a comprehensive analysis of Chromosomal Instability's (CIN) pivotal role in driving metastasis initiation.
Recreating the Tumor Microenvironment In Vitro: Key Challenges and Emerging Solutions for Cancer Research
This article explores the significant challenges researchers face in accurately modeling the complex heterogeneity of the tumor microenvironment (TME) in laboratory settings.
Deciphering Cellular Conversations: A Comprehensive Guide to CellChat for Cell-Cell Communication Analysis
This comprehensive guide provides researchers, scientists, and drug development professionals with a detailed roadmap for leveraging the CellChat R package.
Decoding the Tumor Microenvironment: A Guide to Cell-Cell Communication Networks in Breast Cancer
This article provides a comprehensive resource for researchers and drug development professionals on the complex signaling networks within the breast cancer tumor microenvironment (TME).
Targeting Cancer Stem Cells: Decoding Their Role in Metastasis and Therapeutic Resistance in Solid Tumors
This comprehensive review examines the pivotal role of cancer stem cells (CSCs) in driving tumor metastasis and conferring resistance to conventional and targeted therapies.
Unraveling the Hierarchical Model: How Cancer Stem Cells Drive Tumor Initiation and Progression
This article provides a comprehensive analysis of the cancer stem cell (CSC) hierarchical model, a cornerstone theory explaining tumor initiation and heterogeneity.
CUL3 vs SPOP Mutations in Cancer: Molecular Mechanisms, Clinical Implications, and Therapeutic Targeting Strategies
This review provides a comprehensive comparison of CUL3 and SPOP mutant tumors, focusing on their distinct molecular pathologies, genomic landscapes, and clinical behaviors.
Unraveling CUL3 and SPEN Mutations: Key Drivers in Prostate Cancer Progression and Treatment Resistance
This article provides a comprehensive analysis of recent discoveries linking CUL3 and SPEN mutations to advanced prostate cancer, particularly castration-resistant prostate cancer (CRPC).
Next-Gen Drug Screening: How CSC-Derived Organoids Are Transforming Precision Oncology
This article explores the revolutionary role of cancer stem cell (CSC)-derived organoids in modern drug discovery.
Decoding the Cancer Stem Cell Code: A Comparative Analysis of CSC vs Normal Stem Cell Molecular Signatures for Targeted Therapies
This article provides a comprehensive comparative analysis of the distinct molecular signatures that define Cancer Stem Cells (CSCs) and normal stem cells.